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Alpenglow Biosciences Unveils LUMI: A Revolutionary Imaging Interface at ABRF 2025

Alpenglow Biosciences

Alpenglow Biosciences, a leader in 3D spatial biology, proudly announces the launch of LUMI, an intuitive user interface designed to integrate smart microscopy into the light-sheet workflow. Attendees of the Association of Biomolecular Resource Facilities (ABRF) 2025 Annual Meeting will get an exclusive first look at LUMI’s capabilities.

LUMI (Light-Sheet User Microscope Interface) is the latest innovation for Alpenglow’s 3D i™ Hybrid Open-Top Light-Sheet (HOTLS) microscope, providing a seamless and user-friendly imaging experience. Built for researchers seeking high-resolution, 3D imaging of biological specimens, LUMI enhances workflow efficiency and data acquisition through its key features:

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  • Intuitive Scan Setup – Streamlined scan configurations allow users to set up imaging parameters effortlessly.
  • Live Preview Mode – Real-time previews provide immediate feedback on scan quality, with Scout Mode offering a wide-field overview for quickly identifying regions of interest, and Zoom Mode delivering high-resolution imaging for capturing intricate details with precision.
  • Seamless Operation – A user friendly experience reduces the learning curve for advanced light-sheet microscopy.
  • Smart Microscopy – Ability to create algorithms for automated region of interest detection and Scout-to-Zoom workflows.

“With LUMI, we’re making high-throughput 3D imaging more accessible than ever,” said Nicholas P. Reder, MD, MPH, CEO founder and co-inventor at Alpenglow Biosciences. “Researchers can now easily navigate complex microscopy workflows with an interface designed for efficiency.”

Source: BusinessWire