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Gusto Global and Crohn’s & Colitis Foundation Expand Partnership to Advance Prognostic and Therapeutic Technologies for IBD

Gusto Global

Gusto Global, LLC announces an expansion of its partnership with the Crohn’s & Colitis Foundation to advance groundbreaking technical development for a prognostic linking predictive microbiome-based biomarkers to sustainable remission.

With inflammatory bowel disease (IBD) affecting nearly 1 in 100 Americans and growing, the need for precision-oriented tools to gain microbiome insights and improve treatment protocols is urgent. Dr. Daniel van der Lelie, CEO of Gusto Global, illustrates the driving force accelerating the collaboration, “Our vision is to provide an unprecedented view into critical IBD biomarkers and equip patients with never-before-seen perspective to monitor disease onset, progression, and treatment response, paving a much clearer path towards interventions that lead to long-term success. Reducing the burden of taking medications that only address symptoms is not a distant goal but an immediate requirement.”

The Crohn’s & Colitis Foundation previously funded development of Gusto’s rigorously defined and systematically profiled community of bacteria aiming to treat IBD by rebalancing a healthy microbiome (Nature Communications). Andres Hurtado-Lorenzo, PhD, VP of Translational Research and IBD Ventures at Crohn’s & Colitis Foundation expressed enthusiasm for this unique strategy, “Through our IBD Ventures investment in Gusto Global, we are catalyzing the advancement of innovative microbiome-based therapeutics. We are excited about the potential of this technology to provide a novel approach to induce sustained remission in patients with IBD.”

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The expansion of the partnership recognizes that the computational platform that enables Gusto’s smart Live Biotherapeutic Product design can be advanced to also confirm microbial biomarkers indicative of IBD pathology and offer actionable patient insights.

Angela Dobes, Vice President, IBD Plexus, Crohn’s & Colitis Foundation, stated, “We are delighted to expand the relationship with Gusto Global to better understand disease progression – an area of high unmet need in IBD – and generate a novel dataset to drive new insights and advance progress towards precision medicine.”

The Crohn’s & Colitis Foundation is providing access to its IBD Plexus platform, one of the world’s most comprehensive collections of IBD data, information, and bio samples. Guided by the patient voice, IBD Plexus unites the research community to answer the most important questions in IBD. This access allows Gusto to further validate the pioneering sequencing and computational capabilities of its Tapestry® platform. Tapestry® aims to provide high-resolution individual microbiome signatures from stool and blood samples – advancing the promise of precision medicine for IBD.

SOURCE: Businesswire