Massive Bio introduced Reticulum Nexus, the company’s most significant technological leap to date: a patient-centric, multi-agent platform engineered to coordinate the full oncology journey, from first contact to last-mile enrollment, across networks operating at global scale.
In an environment where clinical trial access has long been constrained by fragmented data pipelines, site-centric processes, and human-heavy workflows, Reticulum Nexus establishes a unified operating fabric. This next-generation system integrates clinical and operational intelligence to match, enroll, and collect outcomes to build more powerful advanced analytics.
The company’s most recent announcements include:
- Full alignment with the CMS Health Tech Ecosystem, reaffirming its mission to modernize clinical trial access through secure, AI-powered patient-facing technology;
- Key partnership with the largest US cancer-patient advocacy group demonstrated the viability of a patient-first operating model; and
- AI prescreening hubs drew recognition from Cancer Moonshot; and partners such as Precision Cancer Consortium scaled deployments across broad and diverse populations.
“Most systems optimize a single node,” said Selin Kurnaz, PhD, Cofounder & CEO. “Reticulum Nexus will help bring in the world’s first scalable patient journey, and paired with the enablement of AI agents.”
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“Moravec’s Paradox shows us the boundary between repetitive and contextual work,” said Arturo Loaiza-Bonilla, MD, Cofounder & Chief Medical AI Officer. “With Reticulum Nexus, multi-agent, contextual AI handles the operational load so clinicians can focus on human care. Dr. Arturo AI already supports thousands of patients; we can now safely scale to millions.”
“Radiant Core is the control plane that makes agentic AI dependable at production scale,” added Çağatay Çulcuoğlu, Cofounder, CTO & COO, Massive Bio. “SYNERGYAI OS is the routing fabric connecting every workflow. Together, they deliver interoperability, auditability, and real-world performance from day one.”
Inside the Nexus Network
Radiant Core – the control plane focused on data quality, compliance, and agent behavior.
SYNERGYAI OS – the multi-agent operating system
Interoperable Architecture – native FHIR/mCODE integration, governance designed for regulated environments (GDPR, HIPAA).
Modules Available at Launch
- Patient Connect & Clinical Network Apps – Mobile-to-EHR pathways that simplify intake, data flow, and provider workflows.
- Clinical Trial Enabler – Real-time eligibility surfacing with transparent rationales and last-mile enrollment logistics.
- Commercial Intelligence & RWD Explorer – Governed insights for assessing unmet need, feasibility, and real-world outcomes.
- Dr. Arturo AI – Multi-agent patient navigation and clinician support with structured human oversight.
Source: Businesswire